Anti-RNF43 antibody [SAA1758] (STJA0020186)

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STJA0020186
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Covered by St John's Laboratory Guarantee

Host: Mouse
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS
Short Description : Mouse monoclonal antibody anti-E3 Ubiquitin-Protein Ligase Rnf43 is suitable for use in ELISA research applications.
Clonality : Monoclonal
Clone ID : SAA1758
Conjugation: Unconjugated
Isotype: IgG2a
Formulation: 0.01M PBS
Purification: Protein A/G purified from cell culture supernatant
Concentration: 1 mg/mL
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months
Gene Symbol: RNF43
Gene ID: 54894
Uniprot ID: RNF43_HUMAN
Post Translational Modifications Autoubiquitinated.
Function E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradation of Wnt receptor complex components Frizzled. Acts on both canonical and non-canonical Wnt signaling pathway. Along with RSPO2 and ZNRF3, constitutes a master switch that governs limb specification.
Protein Name E3 Ubiquitin-Protein Ligase Rnf43
Ring Finger Protein 43
Ring-Type E3 Ubiquitin Transferase Rnf43
Database Links Reactome: R-HSA-4641263
Reactome: R-HSA-5340588
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Endoplasmic Reticulum Membrane
Nucleus Envelope
According To A Report
May Be Secreted
Alternative Antibody Names Anti-E3 Ubiquitin-Protein Ligase Rnf43 antibody
Anti-Ring Finger Protein 43 antibody
Anti-Ring-Type E3 Ubiquitin Transferase Rnf43 antibody
Anti-RNF43 antibody

Information sourced from Uniprot.org

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