| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-RNASEH1 (1-286) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
RNASEH1 |
| Gene ID: |
246243 |
| Uniprot ID: |
RNH1_HUMAN |
| Immunogen Region: |
1-286 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-286 of human RNASEH1 (NP_002927.2). |
| Immunogen Sequence: |
MSWLLFLAHRVALAALPCRR GSRGFGMFYAVRRGRKTGVF LTWNECRAQVDRFPAARFKK FATEDEAWAFVRKSASPEVS EGHENQHGQESEAKASKRLR EPLDGDGHESAEPYAKHMKP SVEPAPPVSRDTFSYMGDFV VVYTDGCCSSNGRRRPRAGI GVYWGPGHPLNVGIRLPGRQ TNQRAEIHAACKAIEQAKTQ NINKLVLYTDSMFTINGITN WVQGWKKNGWKTSAGKEVI |
| Tissue Specificity | Ubiquitous. |
| Function | Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. Plays a role in RNA polymerase II (RNAp II) transcription termination by degrading R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly(A) site and behind the elongating RNAp II. |
| Protein Name | Ribonuclease H1Rnase H1Ribonuclease H Type Ii |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Ribonuclease H1 antibodyAnti-Rnase H1 antibodyAnti-Ribonuclease H Type Ii antibodyAnti-RNASEH1 antibodyAnti-RNH1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
