Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-RNASE3 (100-160) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:1000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
RNASE3 |
Gene ID: |
6037 |
Uniprot ID: |
ECP_HUMAN |
Immunogen Region: |
100-160 |
Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 100-160 of human RNASE3 (NP_002926.2). |
Immunogen Sequence: |
RSRFRVPLLHCDLINPGAQN ISNCTYADRPGRRFYVVACD NRDPRDSPRYPVVPVHLDTT I |
Function | Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. Promotes E.coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content. |
Protein Name | Eosinophil Cationic ProteinEcpRibonuclease 3Rnase 3 |
Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-6803157 |
Cellular Localisation | SecretedLocated In The Matrix Of Eosinophil Large Specific GranuleWhich Are Released Following Activation By An Immune Stimulus |
Alternative Antibody Names | Anti-Eosinophil Cationic Protein antibodyAnti-Ecp antibodyAnti-Ribonuclease 3 antibodyAnti-Rnase 3 antibodyAnti-RNASE3 antibodyAnti-ECP antibodyAnti-RNS3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance