| Short Description : | Rabbit polyclonal RNASE1 (29-156) antibody for use in WB and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RNASE1 |
| Gene ID: | 6035 |
| Uniprot ID: | RNAS1_HUMAN |
| Immunogen Region: | 29-156 |
| Immunogen Sequence: | KESRAKKFQRQHMDSDSSPS SSSTYCNQMMRRRNMTQGRC KPVNTFVHEPLVDVQNVCFQ EKVTCKNGQGNCYKSNSSMH ITDCRLTNGSRYPNCAYRTS PKERHIIVACEGSPYVPVHF DASVEDST |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 29-156 of human RNASE1 (NP_937875.1). |
| Tissue Specificity | Pancreas and other tissues and body fluids (indicating it may have other physiological functions besides its role in digestion). |
| Post Translational Modifications | N-linked glycans are of complex type. |
| Function | Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single-stranded and double-stranded RNA. |
| Protein Name | Ribonuclease PancreaticHp-RnaseRib-1Rnase Upi-1Ribonuclease 1Rnase 1Ribonuclease ARnase A |
| Database Links | Reactome: R-HSA-9613829Reactome: R-HSA-9615710Reactome: R-HSA-9925561 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Ribonuclease Pancreatic antibodyAnti-Hp-Rnase antibodyAnti-Rib-1 antibodyAnti-Rnase Upi-1 antibodyAnti-Ribonuclease 1 antibodyAnti-Rnase 1 antibodyAnti-Ribonuclease A antibodyAnti-Rnase A antibodyAnti-RNASE1 antibodyAnti-RIB1 antibodyAnti-RNS1 antibody |
Information sourced from Uniprot.org
![Immunofluorescence analysis of HeLa cells using [KO Validated] CDKN2A/p16INK4a Rabbit polyclonal antibody (STJ23076) at dilution of 1:200 (40x lens). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/99355/384261/STJ23076_1__86905.1713152939.jpg?c=1 "Immunofluorescence analysis of HeLa cells using [KO Validated] CDKN2A/p16INK4a Rabbit polyclonal antibody (STJ23076) at dilution of 1:200 (40x lens). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.")
