Anti-RIT1 antibody (170-219 aa) (STJ95514)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human RIT1 at the amino acid range 170-219
General Information
| Short Description | Rabbit polyclonal anti-GTP-binding protein Rit1 (170-219 aa) for use in WB, ELISA and IHC in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA/IHC |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RIT1 |
| Gene ID | 6016 |
| Uniprot ID | RIT1_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human RIT1 at the amino acid range 170-219 |
| Immunogen Region | 170-219 aa |
| Specificity | Rit1 Polyclonal Antibody detects endogenous levels of Rit1 protein. |
Additional Info
| Function | Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and MAPK14 signaling pathways and in NGF-dependent neuronal differentiation. Involved in ELK1 transactivation through the Ras-MAPK signaling cascade that mediates a wide variety of cellular functions, including cell proliferation, survival, and differentiation. |
| Protein Name | Gtp-Binding Protein Rit1Ras-Like Protein Expressed In Many TissuesRas-Like Without Caax Protein 1 |
| Database Links | Reactome: R-HSA-187706 |
| Cellular Localisation | Cell Membrane |
| Alternative Antibody Names | Anti-Gtp-Binding Protein Rit1 antibodyAnti-Ras-Like Protein Expressed In Many Tissues antibodyAnti-Ras-Like Without Caax Protein 1 antibodyAnti-RIT1 antibodyAnti-RIBB antibodyAnti-RIT antibodyAnti-ROC1 antibody |
Information sourced from Uniprot.org