| Host: | Rabbit |
| Applications: | WB/ELISA/IHC |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Ras and Rab interactor 3 (391-440 aa) is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RIN3 |
| Gene ID: | 79890 |
| Uniprot ID: | RIN3_HUMAN |
| Immunogen Region: | 391-440 aa |
| Specificity: | RIN3 Polyclonal Antibody detects endogenous levels of RIN3 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human RIN3 at the amino acid range 391-440 |
| Function | Ras effector protein that functions as a guanine nucleotide exchange (GEF) for RAB5B and RAB31, by exchanging bound GDP for free GTP. Required for normal RAB31 function. |
| Protein Name | Ras And Rab Interactor 3Ras Interaction/Interference Protein 3 |
| Database Links | Reactome: R-HSA-8876198 |
| Cellular Localisation | CytoplasmCytoplasmic VesicleEarly EndosomeActivation Of Tyrosine Phosphorylation Signaling Induces Translocation To Cytoplasmic Vesicles |
| Alternative Antibody Names | Anti-Ras And Rab Interactor 3 antibodyAnti-Ras Interaction/Interference Protein 3 antibodyAnti-RIN3 antibody |
Information sourced from Uniprot.org