| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Rab-interacting lysosomal protein (70-150 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RILP |
| Gene ID: | 83547 |
| Uniprot ID: | RILP_HUMAN |
| Immunogen Region: | 70-150 aa |
| Specificity: | RILP Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 70-150 |
| Function | Rab effector playing a role in late endocytic transport to degradative compartments. Involved in the regulation of lysosomal morphology and distribution. Induces recruitment of dynein-dynactin motor complexes to Rab7A-containing late endosome and lysosome compartments. Promotes centripetal migration of phagosomes and the fusion of phagosomes with the late endosomes and lysosomes. |
| Protein Name | Rab-Interacting Lysosomal Protein |
| Database Links | Reactome: R-HSA-2132295 |
| Cellular Localisation | Late Endosome MembraneLysosome MembraneCytoplasmic VesiclePhagosome MembraneAssociated With Late EndosomalLysosomal And Phagosomal MembranesThe Interaction With Rab7a Is Necessary For Its Recruitment To Phagosomes |
| Alternative Antibody Names | Anti-Rab-Interacting Lysosomal Protein antibodyAnti-RILP antibodyAnti-PP10141 antibody |
Information sourced from Uniprot.org