Anti-RHOD antibody (113-162 aa) (STJ95444)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human RHOD at the amino acid range 113-162
General Information
| Short Description | Rabbit polyclonal anti-Rho-related GTP-binding protein RhoD (113-162 aa) for use in WB, ELISA and IHC in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA/IHC |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RHOD |
| Gene ID | 29984 |
| Uniprot ID | RHOD_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human RHOD at the amino acid range 113-162 |
| Immunogen Region | 113-162 aa |
| Specificity | Rho D Polyclonal Antibody detects endogenous levels of Rho D protein. |
Additional Info
| Function | Involved in endosome dynamics. May coordinate membrane transport with the function of the cytoskeleton. Involved in the internalization and trafficking of activated tyrosine kinase receptors such as PDGFRB. Participates in the reorganization of actin cytoskeleton.the function seems to involve WHAMM and includes regulation of filopodia formation and actin filament bundling. Can modulate the effect of DAPK3 in reorganization of actin cytoskeleton and focal adhesion dissolution. |
| Protein Name | Rho-Related Gtp-Binding Protein RhodRho-Related Protein Hp1Rhohp1 |
| Database Links | Reactome: R-HSA-5663220Reactome: R-HSA-9013405 |
| Cellular Localisation | Cell MembraneLipid-AnchorCytoplasmic SideEarly EndosomeColocalizes With Rab5 To Early Endosomes |
| Alternative Antibody Names | Anti-Rho-Related Gtp-Binding Protein Rhod antibodyAnti-Rho-Related Protein Hp1 antibodyAnti-Rhohp1 antibodyAnti-RHOD antibodyAnti-ARHD antibody |
Information sourced from Uniprot.org