| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: |
RHOBTB3 |
| Gene ID: |
22836 |
| Uniprot ID: |
RHBT3_HUMAN |
| Immunogen Region: |
1-230 aa |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human RHOBTB3 (NP_055714.3). |
| Immunogen Sequence: |
MSIHIVALGNEGDTFHQDNR PSGLIRTYLGRSPLVSGDES SLLLNAASTVARPVFTEYQA SAFGNVKLVVHDCPVWDIFD SDWYTSRNLIGGADIIVIKY NVNDKFSFHEVKDNYIPVIK RALNSVPVIIAAVGTRQNEE LPCTCPLCTSDRGSCVSTTE GIQLAKELGATYLELHSLDD FYIGKYFGGVLEYFMIQALN QKTSEKMKKRKMSNSFHGIR PPQLEQPEKM |
| Tissue Specificity | Ubiquitous. Highly expressed in neural and cardiac tissues, pancreas, placenta and testis. |
| Function | Rab9-regulated ATPase required for endosome to Golgi transport. Involved in transport vesicle docking at the Golgi complex, possibly by participating in release M6PRBP1/TIP47 from vesicles to permit their efficient docking and fusion at the Golgi. Specifically binds Rab9, but not other Rab proteins. Has low intrinsic ATPase activity due to autoinhibition, which is relieved by Rab9. |
| Protein Name | Rho-Related Btb Domain-Containing Protein 3 |
| Database Links | Reactome: R-HSA-6811440Reactome: R-HSA-9706019 |
| Cellular Localisation | Golgi Apparatus |
| Alternative Antibody Names | Anti-Rho-Related Btb Domain-Containing Protein 3 antibodyAnti-RHOBTB3 antibodyAnti-KIAA0878 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
