Anti-RHBG antibody (Internal) (STJ72342)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-RHBG (Internal) is suitable for use in ELISA and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/IHC |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Dog/Pig |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:2000.WB: Preliminary experiments in Human, Mouse and Rat Kidney lysates gave no specific signal but low background (at antibody concentration up to 1µg/ml).IHC: Paraffin embedded Human Kidn |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | RHBG |
| Gene ID | 57127 |
| Uniprot ID | RHBG_HUMAN |
| Accession Number | NP_065140.3 |
| Immunogen Region | Internal |
| Immunogen Sequence | PQLEKSKHRQ |
Additional Info
| Post Translational Modifications | N-glycosylated. |
| Function | Ammonium transporter involved in the maintenance of acid-base homeostasis. Transports ammonium and its related derivative methylammonium across the basolateral plasma membrane of epithelial cells likely contributing to renal transepithelial ammonia transport and ammonia metabolism. May transport either NH4(+) or NH3 ammonia species predominantly mediating an electrogenic NH4(+) transport. May act as a CO2 channel providing for renal acid secretion. |
| Protein Name | Ammonium Transporter Rh Type BRhesus Blood Group Family Type B GlycoproteinRh Family Type B GlycoproteinRh Type B Glycoprotein |
| Database Links | Reactome: R-HSA-444411 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinBasolateral Cell Membrane |
| Alternative Antibody Names | Anti-Ammonium Transporter Rh Type B antibodyAnti-Rhesus Blood Group Family Type B Glycoprotein antibodyAnti-Rh Family Type B Glycoprotein antibodyAnti-Rh Type B Glycoprotein antibodyAnti-RHBG antibody |
Information sourced from Uniprot.org