| Short Description : | Rabbit polyclonal anti-Inactive rhomboid protein 2 for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RHBDF2 |
| Gene ID: | 79651 |
| Uniprot ID: | RHDF2_HUMAN |
| Immunogen: | Synthesized peptide derived from human RHBDF2 |
| Specificity: | This antibody detects endogenous levels of RHBDF2 at Human, Mouse |
| Function | Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own. |
| Protein Name | Inactive Rhomboid Protein 2Irhom2Rhomboid 5 Homolog 2Rhomboid Family Member 2Rhomboid Veinlet-Like Protein 5Rhomboid Veinlet-Like Protein 6 |
| Database Links | Reactome: R-HSA-9662834 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane ProteinCell Membrane |
| Alternative Antibody Names | Anti-Inactive Rhomboid Protein 2 antibodyAnti-Irhom2 antibodyAnti-Rhomboid 5 Homolog 2 antibodyAnti-Rhomboid Family Member 2 antibodyAnti-Rhomboid Veinlet-Like Protein 5 antibodyAnti-Rhomboid Veinlet-Like Protein 6 antibodyAnti-RHBDF2 antibodyAnti-IRHOM2 antibodyAnti-RHBDL5 antibodyAnti-RHBDL6 antibody |
Information sourced from Uniprot.org