| Tissue Specificity | Found in the epidermis and esophageal epithelium. |
| Function | Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own. |
| Protein Name | Inactive Rhomboid Protein 2Irhom2Rhomboid 5 Homolog 2Rhomboid Family Member 2Rhomboid Veinlet-Like Protein 5Rhomboid Veinlet-Like Protein 6 |
| Database Links | Reactome: R-HSA-9662834 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane ProteinCell Membrane |
| Alternative Antibody Names | Anti-Inactive Rhomboid Protein 2 antibodyAnti-Irhom2 antibodyAnti-Rhomboid 5 Homolog 2 antibodyAnti-Rhomboid Family Member 2 antibodyAnti-Rhomboid Veinlet-Like Protein 5 antibodyAnti-Rhomboid Veinlet-Like Protein 6 antibodyAnti-RHBDF2 antibodyAnti-IRHOM2 antibodyAnti-RHBDL5 antibodyAnti-RHBDL6 antibody |
Information sourced from Uniprot.org
