| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: |
RGS6 |
| Gene ID: |
9628 |
| Uniprot ID: |
RGS6_HUMAN |
| Immunogen Region: |
215-320 aa |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 215-320 of human RGS6 (NP_004287.3). |
| Immunogen Sequence: |
MDIRKCRRLKNPQKVKKSVY GVTEESQAQSPVHVLSQPIR KTTKEDIRKQITFLNAQIDR HCLKMSKVAESLIAYTEQYV EYDPLITPAEPSNPWISDDV ALWDIE |
| Function | Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. The RGS6/GNB5 dimer enhances GNAO1 GTPase activity. |
| Protein Name | Regulator Of G-Protein Signaling 6Rgs6S914 |
| Database Links | Reactome: R-HSA-418594Reactome: R-HSA-6814122 |
| Cellular Localisation | CytoplasmCytosolMembranePeripheral Membrane ProteinNucleusCell MembraneInteraction With Gnb5 Mediates Translocation To The Nucleus |
| Alternative Antibody Names | Anti-Regulator Of G-Protein Signaling 6 antibodyAnti-Rgs6 antibodyAnti-S914 antibodyAnti-RGS6 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
