| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Regulator of cell cycle RGCC (5-55) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:1000-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RGCC |
| Gene ID: | 28984 |
| Uniprot ID: | RGCC_HUMAN |
| Immunogen Region: | 5-55 |
| Specificity: | This antibody detects endogenous levels of human RGCC |
| Immunogen: | Synthesized peptide derived from human RGCC AA range: 5-55 |
| Function | Modulates the activity of cell cycle-specific kinases. Enhances CDK1 activity. May contribute to the regulation of the cell cycle. May inhibit growth of glioma cells by promoting arrest of mitotic progression at the G2/M transition. Fibrogenic factor contributing to the pathogenesis of renal fibrosis through fibroblast activation. |
| Protein Name | Regulator Of Cell Cycle RgccResponse Gene To Complement 32 ProteinRgc-32 |
| Database Links | Reactome: R-HSA-6804115 |
| Cellular Localisation | CytoplasmNucleusCytoskeletonMicrotubule Organizing CenterCentrosomeCytoplasmic In Unstimulated CellsNuclear After Activation By ComplementAssociated With The Centrosome During Prometaphase And Metaphase |
| Alternative Antibody Names | Anti-Regulator Of Cell Cycle Rgcc antibodyAnti-Response Gene To Complement 32 Protein antibodyAnti-Rgc-32 antibodyAnti-RGCC antibodyAnti-C13orf15 antibodyAnti-RGC32 antibody |
Information sourced from Uniprot.org