Anti-RFPL1 antibody (160-240 aa) (STJ191311)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 160-240
General Information
| Short Description | Rabbit polyclonal anti-Ret finger protein-like 1 (160-240 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RFPL1 |
| Gene ID | 5988 |
| Uniprot ID | RFPL1_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 160-240 |
| Immunogen Region | 160-240 aa |
| Specificity | RFPL1 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Post Translational Modifications | Phosphorylated by PKC and CDK1. The antiproliferative effect seems to be positively regulated by PKC phosphorylation and negatively by CDK1 phosphorylation. |
| Function | Negatively regulates the G2-M phase transition, possibly by promoting cyclin B1/CCNB1 and CDK1 proteasomal degradation and thereby preventing their accumulation during interphase. |
| Protein Name | Ret Finger Protein-Like 1Ring Finger Protein 78 |
| Database Links | |
| Cellular Localisation | CytoplasmNucleusA Higher Concentration Is Observed In The Cytoplasm Compared To The Nucleus |
| Alternative Antibody Names | Anti-Ret Finger Protein-Like 1 antibodyAnti-Ring Finger Protein 78 antibodyAnti-RFPL1 antibodyAnti-RFPL1L antibodyAnti-RNF78 antibody |
Information sourced from Uniprot.org