| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Ret finger protein-like 1 (160-240 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RFPL1 |
| Gene ID: | 5988 |
| Uniprot ID: | RFPL1_HUMAN |
| Immunogen Region: | 160-240 aa |
| Specificity: | RFPL1 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 160-240 |
| Post Translational Modifications | Phosphorylated by PKC and CDK1. The antiproliferative effect seems to be positively regulated by PKC phosphorylation and negatively by CDK1 phosphorylation. |
| Function | Negatively regulates the G2-M phase transition, possibly by promoting cyclin B1/CCNB1 and CDK1 proteasomal degradation and thereby preventing their accumulation during interphase. |
| Protein Name | Ret Finger Protein-Like 1Ring Finger Protein 78 |
| Database Links | |
| Cellular Localisation | CytoplasmNucleusA Higher Concentration Is Observed In The Cytoplasm Compared To The Nucleus |
| Alternative Antibody Names | Anti-Ret Finger Protein-Like 1 antibodyAnti-Ring Finger Protein 78 antibodyAnti-RFPL1 antibodyAnti-RFPL1L antibodyAnti-RNF78 antibody |
Information sourced from Uniprot.org
