| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | REV3L |
| Gene ID: | 5980 |
| Uniprot ID: | REV3L_HUMAN |
| Immunogen Region: | 220-500 aa |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 220-500 of human REV3L (NP_002903.3). |
| Immunogen Sequence: | PSSLILEGVEPQSTCELEVD AVAADILNRLDIEAQIGGNP GLQAIWEDEKQRRRNRNETS QMSQPESQDHRFVPATESEK KFQKRLQEILKQNDFSVTLS GSVDYSDGSQEFSAELTLHS EVLSPEMLQCTPANMVEVHK DKESSKGHTRHKVEEALINE EAILNLMENSQTFQPLTQRL SESPVFMDSSPDEALVHLLA GLESDGYRGERNRMPSPCRS FGNNKYPQNSDDEENEPQI |
| Tissue Specificity | Ubiquitously expressed. |
| Function | Catalytic subunit of the DNA polymerase zeta complex, an error-prone polymerase specialized in translesion DNA synthesis (TLS). Lacks an intrinsic 3'-5' exonuclease activity and thus has no proofreading function. |
| Protein Name | Dna Polymerase Zeta Catalytic SubunitProtein Reversionless 3-LikeRev3-LikeHrev3 |
| Database Links | Reactome: R-HSA-110312Reactome: R-HSA-5655862Reactome: R-HSA-5656121 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Dna Polymerase Zeta Catalytic Subunit antibodyAnti-Protein Reversionless 3-Like antibodyAnti-Rev3-Like antibodyAnti-Hrev3 antibodyAnti-REV3L antibodyAnti-POLZ antibodyAnti-REV3 antibody |
Information sourced from Uniprot.org