![Anti-Retinoblastoma Gene Protein antibody [13A10] (STJ16101790)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/152296/347143/STJ16101790_1__03138.1681999415.jpg?c=1 "Anti-Retinoblastoma Gene Protein antibody [13A10] (STJ16101790)")
![Anti-Retinoblastoma Gene Protein antibody [13A10] (STJ16101790)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/152296/347143/STJ16101790_1__03138.1681999415.jpg?c=1 "Anti-Retinoblastoma Gene Protein antibody [13A10] (STJ16101790)")
Anti-Retinoblastoma Gene Protein antibody [13A10] (STJ16101790)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenRecombinant prokaryotic protein corresponding to a portion of the N-terminal region of the retinoblastoma gene product.
General Information
| Short Description | Mouse monoclonal anti-Retinoblastoma Gene Protein for use in IHC-P, IHC-F and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P/IHC-F/WB |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 13A10 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Dilution Range | IHC-P 1:25-1:50IHC-FWB 1:250 |
| Formulation | Tissue culture supernatant with 15mM sodium azide |
| Storage Instruction | Store at 2-8°C for up to 1-year, upon receipt. |
Target Information
| Immunogen | Recombinant prokaryotic protein corresponding to a portion of the N-terminal region of the retinoblastoma gene product. |
Additional Info
| Background | Retinoblastoma (Rb) is a rare tumor of the retina associated with mutations of chromosome 13. The nuclear phosphoprotein encoded by the Rb tumor suppressor gene is present in many cells and may indirectly regulate cell growth by activating the transcription factor ATF-2. Activation of ATF-2 initiates expression of TGF-beta2, which in turn inhibits transcription of genes affecting cell growth. Bilateral mutation of the Rb gene may potentially play a role in the development of a number of malignant tumors. |
Information sourced from Uniprot.org