Anti-REPIN1 antibody (376-567 aa) [SRM5297] (STJ11107200)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal REPIN1 (376-567 aa) antibody for use in WB, IHC-P and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SRM5297 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:10000-1:48000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3. |
Target Information
| Gene Symbol | REPIN1 |
| Gene ID | 29803 |
| Uniprot ID | REPI1_HUMAN |
| Immunogen Region | 376-567 aa |
| Immunogen Sequence | SCDDCGRSFRLERFLRAHQR QHTGERPFTCAECGKNFGKK THLVAHSRVHSGERPFACEE CGRRFSQGSHLAAHRRDHAP DRPFVCPDCGKAFRHKPYLA AHRRIHTGEKPYVCPDCGKA FSQKSNLVSHRRIHTGERPY ACPDCDRSFSQKSNLITHRK SHIRDGAFCCAICGQTFDDE ERLLAHQKKHDV |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 376-567 of human REPIN1 (NP_037532.2). |
Additional Info
| Tissue Specificity | Expressed in adipose tissue and bone tissue. |
| Function | Sequence-specific double-stranded DNA-binding protein. Binds ATT-rich and T-rich DNA sequences and facilitates DNA bending. May regulate the expression of genes involved in cellular fatty acid import, including SCARB1/CD36, and genes involved in lipid droplet formation. May regulate the expression of LCN2, and thereby influence iron metabolism and apoptosis-related pathways. May regulate the expression of genes involved in glucose transport. |
| Protein Name | Dna-Binding Protein Repin160 Kda Origin-Specific Dna-Binding Protein60 Kda Replication Initiation Region ProteinAtt-Binding ProteinDhfr Oribeta-Binding Protein Rip60Zinc Finger Protein 464 |
| Database Links | |
| Cellular Localisation | NucleusCytoplasmCytosol |
| Alternative Antibody Names | Anti-Dna-Binding Protein Repin1 antibodyAnti-60 Kda Origin-Specific Dna-Binding Protein antibodyAnti-60 Kda Replication Initiation Region Protein antibodyAnti-Att-Binding Protein antibodyAnti-Dhfr Oribeta-Binding Protein Rip60 antibodyAnti-Zinc Finger Protein 464 antibodyAnti-REPIN1 antibodyAnti-RIP60 antibodyAnti-ZNF464 antibody |
Information sourced from Uniprot.org