| Host: | Rabbit |
| Applications: | IHC/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-REEP6 (2-50 aa) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Lyophilised |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB (confirmed by recombinant protein). A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | REEP6 |
| Gene ID: | 92840 |
| Uniprot ID: | REEP6_HUMAN |
| Immunogen Region: | 2-50 aa |
| Specificity: | Specific for REEP6 |
| Immunogen: | A synthetic peptide from aa region 2-50 of human REEP6 conjugated to blue carrier protein was used as the antigen. |
| Function | Required for correct function and survival of retinal photoreceptors. Required for retinal development. In rod photoreceptors, facilitates stability and/or trafficking of guanylate cyclases and is required to maintain endoplasmic reticulum and mitochondrial homeostasis. May play a role in clathrin-coated intracellular vesicle trafficking of proteins from the endoplasmic reticulum to the retinal rod plasma membrane. |
| Protein Name | Receptor Expression-Enhancing Protein 6Polyposis Locus Protein 1-Like 1 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane ProteinCytoplasmic VesicleClathrin-Coated Vesicle Membrane |
| Alternative Antibody Names | Anti-Receptor Expression-Enhancing Protein 6 antibodyAnti-Polyposis Locus Protein 1-Like 1 antibodyAnti-REEP6 antibodyAnti-C19orf32 antibodyAnti-DP1L1 antibody |
Information sourced from Uniprot.org