Anti-Recombinant-ZIC1 antibody [RM2G78] (STJA0025646)

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STJA0025646
€386.88 - €590.63
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Host: Rabbit
Applications: FC/IF/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal antibody anti-Recombinant-Zinc Finger Protein Zic 1 is suitable for use in Flow Cytometry, Immunofluorescence and Western Blot research applications.
Clonality : Monoclonal
Clone ID : RM2G78
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide
Purification: Protein A/G purified from cell culture supernatant
Dilution Range: FCM: 1:20-1:100, IF: 1:50-1:200, WB: 1:1000-1:2000
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: ZIC1
Gene ID: 7545
Uniprot ID: ZIC1_HUMAN
Function Acts as a transcriptional activator. Involved in neurogenesis. Plays important roles in the early stage of organogenesis of the CNS, as well as during dorsal spinal cord development and maturation of the cerebellum. Involved in the spatial distribution of mossy fiber (MF) neurons within the pontine gray nucleus (PGN). Plays a role in the regulation of MF axon pathway choice. Promotes MF migration towards ipsilaterally-located cerebellar territories. May have a role in shear flow mechanotransduction in osteocytes. Retains nuclear GLI1 and GLI3 in the cytoplasm. Binds to the minimal GLI-consensus sequence 5'-TGGGTGGTC-3'.
Protein Name Zinc Finger Protein Zic 1
Zinc Finger Protein 201
Zinc Finger Protein Of The Cerebellum 1
Database Links Reactome: R-HSA-9834899
Reactome: R-HSA-9856649
Cellular Localisation Nucleus
Cytoplasm
Localizes In The Cytoplasm In Presence Of Mdfic Overexpression
Alternative Antibody Names Anti-Zinc Finger Protein Zic 1 antibody
Anti-Zinc Finger Protein 201 antibody
Anti-Zinc Finger Protein Of The Cerebellum 1 antibody
Anti-ZIC1 antibody
Anti-ZIC antibody
Anti-ZNF201 antibody

Information sourced from Uniprot.org