Anti-Recombinant-VWF antibody [RM1J62] (STJA0023452)

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STJA0023452
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Host: Rabbit
Applications: IHC/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal antibody anti-Recombinant-Von Willebrand Factor is suitable for use in Immunohistochemistry and Western Blot research applications.
Clonality : Monoclonal
Clone ID : RM1J62
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.01M PBS
Purification: Protein A/G purified from cell culture supernatant
Dilution Range: IHC: 1:100-1:200
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: VWF
Gene ID: 7450
Uniprot ID: VWF_HUMAN
Post Translational Modifications All cysteine residues are involved in intrachain or interchain disulfide bonds. N- and O-glycosylated.
Function Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma.
Protein Name Von Willebrand Factor
Vwf Cleaved Into - Von Willebrand Antigen 2
Von Willebrand Antigen Ii
Database Links Reactome: R-HSA-114608
Reactome: R-HSA-140837
Reactome: R-HSA-216083
Reactome: R-HSA-354192
Reactome: R-HSA-354194
Reactome: R-HSA-372708
Reactome: R-HSA-430116
Reactome: R-HSA-5674135
Reactome: R-HSA-6802946
Reactome: R-HSA-6802948
Reactome: R-HSA-6802952
Reactome: R-HSA-6802955
Reactome: R-HSA-75892
Reactome: R-HSA-76009
Reactome: R-HSA-9649948
Reactome: R-HSA-9656223
Reactome: R-HSA-9672391
Reactome: R-HSA-9672393
Reactome: R-HSA-9845619
Reactome: R-HSA-9845620
Reactome: R-HSA-9845621
Reactome: R-HSA-9845622
Reactome: R-HSA-9846298
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Localized To Storage Granules
Alternative Antibody Names Anti-Von Willebrand Factor antibody
Anti-Vwf Cleaved Into - Von Willebrand Antigen 2 antibody
Anti-Von Willebrand Antigen Ii antibody
Anti-VWF antibody
Anti-F8VWF antibody

Information sourced from Uniprot.org