Anti-Recombinant-VGAT antibody (N-Term) [L118/80] {FL550 Ex: 550 nm, Em: 575 nm} (STJA0040501)

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STJA0040501-200
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Host: Chicken
Applications: ICC/IHC
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Chicken monoclonal anti-Recombinant-VGAT (N-Term) for use in ICC and IHC in Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : L118/80
Conjugation: FL550 Ex: 550 nm, Em: 575 nm
Isotype: IgY
Formulation: 1X PBS, 0.05% Sodium Azide pH 7.4
Purification: Purified by affinity chromatography
Concentration: 0.5 mg/mL
Dilution Range: IHC 1:100
ICC 1:100
Storage Instruction: Aliquot and store at ≤-20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Gene Symbol: Slc32a1
Gene ID: 22348
Uniprot ID: VIAAT_MOUSE
Immunogen Region: N-Term
Specificity: No cross-reactivity reported
Immunogen: Fusion protein amino acids 1-133 (cytoplasmic N-terminus) of mouse VGAT (accession number O35633) produced recombinantly in E. Coli
Immunogen Sequence: Mouse
Function Antiporter that exchanges vesicular protons for cytosolic 4-aminobutanoate or to a lesser extend glycine, thus allowing their secretion from nerve terminals. The transport is equally dependent on the chemical and electrical components of the proton gradient. May also transport beta-alanine. Acidification of GABAergic synaptic vesicles is a prerequisite for 4-aminobutanoate uptake.
Protein Name Vesicular Inhibitory Amino Acid Transporter
Solute Carrier Family 32 Member 1
Vesicular Gaba And Glycine Transporter
Vesicular Gaba Transporter
Mvgat
Mviaat
Database Links Reactome: R-MMU-425393
Reactome: -MMU-888590
Cellular Localisation Cytoplasmic Vesicle Membrane
Multi-Pass Membrane Protein
Presynapse
Presents In Glycine-
Gaba- Or Gaba- And Glycine-Containing Boutons
Alternative Antibody Names Anti-Vesicular Inhibitory Amino Acid Transporter antibody
Anti-Solute Carrier Family 32 Member 1 antibody
Anti-Vesicular Gaba And Glycine Transporter antibody
Anti-Vesicular Gaba Transporter antibody
Anti-Mvgat antibody
Anti-Mviaat antibody
Anti-Slc32a1 antibody
Anti-Vgat antibody
Anti-Viaat antibody

Information sourced from Uniprot.org

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