| Host: |
Rabbit |
| Applications: |
IF/IHC/WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : |
Rabbit monoclonal antibody anti-Recombinant-Transcription Factor Ap-2 Gamma is suitable for use in Immunofluorescence, Immunohistochemistry and Western Blot research applications. |
| Clonality : |
Monoclonal |
| Clone ID : |
RM2S22 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide |
| Purification: |
Protein A/G purified from cell culture supernatant |
| Dilution Range: |
IF: 1:50-1:200, IHC: 1:50-1:100, WB: 1:500-1:1000 |
| Storage Instruction: |
Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
| Function | Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer. |
| Protein Name | Transcription Factor Ap-2 GammaAp2-GammaActivating Enhancer-Binding Protein 2 GammaTranscription Factor Erf-1 |
| Database Links | Reactome: R-HSA-3232118Reactome: R-HSA-8866904Reactome: R-HSA-8866906Reactome: R-HSA-8866907Reactome: R-HSA-8866910Reactome: R-HSA-8866911Reactome: R-HSA-9827857Reactome: R-HSA-9834899 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transcription Factor Ap-2 Gamma antibodyAnti-Ap2-Gamma antibodyAnti-Activating Enhancer-Binding Protein 2 Gamma antibodyAnti-Transcription Factor Erf-1 antibodyAnti-TFAP2C antibody |
Information sourced from Uniprot.org
