| Host: | Rabbit |
| Applications: | IF/WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit monoclonal antibody anti-Recombinant-Rna-Binding Protein 3 is suitable for use in Immunofluorescence and Western Blot research applications. |
| Clonality : | Monoclonal |
| Clone ID : | RM2B60 |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide |
| Purification: | Protein A/G purified from cell culture supernatant |
| Dilution Range: | IF: 1:50-1:200, WB: 1:500-1:1000 |
| Storage Instruction: | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
| Gene Symbol: | RBM3 |
| Gene ID: | 5935 |
| Uniprot ID: | RBM3_HUMAN |
| Function | Cold-inducible mRNA binding protein that enhances global protein synthesis at both physiological and mild hypothermic temperatures. Reduces the relative abundance of microRNAs, when overexpressed. Enhances phosphorylation of translation initiation factors and active polysome formation. |
| Protein Name | Rna-Binding Protein 3Rna-Binding Motif Protein 3Rnpl |
| Cellular Localisation | NucleusCytoplasmCell ProjectionDendriteLocalizes In Mrna Granules In Dentrites |
| Alternative Antibody Names | Anti-Rna-Binding Protein 3 antibodyAnti-Rna-Binding Motif Protein 3 antibodyAnti-Rnpl antibodyAnti-RBM3 antibodyAnti-RNPL antibody |
Information sourced from Uniprot.org
![Western blot analysis of lysates from wild type (WT) and RBM3 knockout (KO) 293T cells, using [KO Validated] RBM3 Rabbit polyclonal antibody (STJ11100843) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3min.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/89777/358248/STJ11100843_1__06496.1713122583.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and RBM3 knockout (KO) 293T cells, using [KO Validated] RBM3 Rabbit polyclonal antibody (STJ11100843) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3min.")
