Host: | Rabbit |
Applications: | IHC/IP/WB |
Reactivity: | Human/Rat/Hamster |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit monoclonal antibody anti-Recombinant-Paxillin is suitable for use in Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
Clonality : | Monoclonal |
Clone ID : | RM1X24 |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | 0.01M PBS |
Purification: | Protein A/G purified from cell culture supernatant |
Dilution Range: | IHC: 1:50-1:100 |
Storage Instruction: | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Gene Symbol: | PXN |
Gene ID: | 5829 |
Uniprot ID: | PAXI_HUMAN |
Function | Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Recruits other proteins such as TRIM15 to focal adhesion. |
Protein Name | Paxillin |
Database Links | Reactome: R-HSA-180292Reactome: R-HSA-4420097Reactome: R-HSA-445355Reactome: R-HSA-446343Reactome: R-HSA-446388Reactome: R-HSA-8849471 |
Cellular Localisation | CytoplasmCytoskeletonCell JunctionFocal AdhesionCell CortexColocalizes With Integrins At The Cell PeripheryColocalize With Pxn To Membrane Ruffles And The Leading Edge Of Migrating Cells |
Alternative Antibody Names | Anti-Paxillin antibodyAnti-PXN antibody |
Information sourced from Uniprot.org