| Function | Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway. |
| Protein Name | Prostaglandin E Synthase 3Cytosolic Prostaglandin E2 SynthaseCpgesHsp90 Co-ChaperoneProgesterone Receptor Complex P23Telomerase-Binding Protein P23 |
| Database Links | Reactome: R-HSA-2162123Reactome: R-HSA-3371497Reactome: R-HSA-3371511Reactome: R-HSA-3371568Reactome: R-HSA-8937144Reactome: R-HSA-8939211Reactome: R-HSA-9018519Reactome: R-HSA-9679191 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Prostaglandin E Synthase 3 antibodyAnti-Cytosolic Prostaglandin E2 Synthase antibodyAnti-Cpges antibodyAnti-Hsp90 Co-Chaperone antibodyAnti-Progesterone Receptor Complex P23 antibodyAnti-Telomerase-Binding Protein P23 antibodyAnti-PTGES3 antibodyAnti-P23 antibodyAnti-TEBP antibody |
Information sourced from Uniprot.org
