Function | May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3. |
Protein Name | Macrophage MetalloelastaseMmeMacrophage ElastaseMeHmeMatrix Metalloproteinase-12Mmp-12 |
Database Links | Reactome: R-HSA-1442490Reactome: R-HSA-1474228 |
Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
Alternative Antibody Names | Anti-Macrophage Metalloelastase antibodyAnti-Mme antibodyAnti-Macrophage Elastase antibodyAnti-Me antibodyAnti-Hme antibodyAnti-Matrix Metalloproteinase-12 antibodyAnti-Mmp-12 antibodyAnti-MMP12 antibodyAnti-HME antibody |
Information sourced from Uniprot.org