Anti-Recombinant-LGI1 antibody [RM1G79] (STJA0023271)

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STJA0023271
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Covered by St John's Laboratory Guarantee

Host: Rabbit
Applications: IHC/IP/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal antibody anti-Recombinant-Leucine-Rich Glioma-Inactivated Protein 1 is suitable for use in Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
Clonality : Monoclonal
Clone ID : RM1G79
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.01M PBS
Purification: Protein A/G purified from cell culture supernatant
Dilution Range: IHC: 1:100-1:200
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: LGI1
Gene ID: 9211
Uniprot ID: LGI1_HUMAN
Post Translational Modifications Glycosylated.
Function Regulates voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1. It slows down channel inactivation by precluding channel closure mediated by the KCNAB1 subunit. Ligand for ADAM22 that positively regulates synaptic transmission mediated by AMPA-type glutamate receptors. Plays a role in suppressing the production of MMP1/3 through the phosphatidylinositol 3-kinase/ERK pathway. May play a role in the control of neuroblastoma cell survival.
Protein Name Leucine-Rich Glioma-Inactivated Protein 1
Epitempin-1
Database Links Reactome: R-HSA-5682910
Cellular Localisation Secreted
Synapse
Cytoplasm
Isoform 1: Golgi Apparatus
Isoform 2: Endoplasmic Reticulum
Alternative Antibody Names Anti-Leucine-Rich Glioma-Inactivated Protein 1 antibody
Anti-Epitempin-1 antibody
Anti-LGI1 antibody
Anti-EPT antibody
Anti-UNQ775 antibody
Anti-PRO1569 antibody

Information sourced from Uniprot.org

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