| Host: |
Rabbit |
| Applications: |
IF/WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : |
Rabbit monoclonal antibody anti-Recombinant-Laminin Subunit Alpha-3 is suitable for use in Immunofluorescence and Western Blot research applications. |
| Clonality : |
Monoclonal |
| Clone ID : |
RM2H55 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide |
| Purification: |
Protein A/G purified from cell culture supernatant |
| Dilution Range: |
IF: 1:50-1:200, WB: 1:1000-1:2000 |
| Storage Instruction: |
Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
| Function | Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminin-5 is thought to be involved in (1) cell adhesion via integrin alpha-3/beta-1 in focal adhesion and integrin alpha-6/beta-4 in hemidesmosomes, (2) signal transduction via tyrosine phosphorylation of pp125-FAK and p80, (3) differentiation of keratinocytes. |
| Protein Name | Laminin Subunit Alpha-3Epiligrin 170 Kda SubunitE170Epiligrin Subunit AlphaKalinin Subunit AlphaLaminin-5 Subunit AlphaLaminin-6 Subunit AlphaLaminin-7 Subunit AlphaNicein Subunit Alpha |
| Database Links | Reactome: R-HSA-1474228Reactome: R-HSA-2022090Reactome: R-HSA-2214320Reactome: R-HSA-3000157Reactome: R-HSA-3000171Reactome: R-HSA-3000178Reactome: R-HSA-446107Reactome: R-HSA-8874081 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixBasement MembraneMajor Component |
| Alternative Antibody Names | Anti-Laminin Subunit Alpha-3 antibodyAnti-Epiligrin 170 Kda Subunit antibodyAnti-E170 antibodyAnti-Epiligrin Subunit Alpha antibodyAnti-Kalinin Subunit Alpha antibodyAnti-Laminin-5 Subunit Alpha antibodyAnti-Laminin-6 Subunit Alpha antibodyAnti-Laminin-7 Subunit Alpha antibodyAnti-Nicein Subunit Alpha antibodyAnti-LAMA3 antibodyAnti-LAMNA antibody |
Information sourced from Uniprot.org
