Anti-Recombinant-IgG2 antibody [RM2L37] (STJA0026001)

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STJA0026001
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Host: Rabbit
Applications: IF/IHC/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal antibody anti-Recombinant-Immunoglobulin Heavy Constant Gamma 2 is suitable for use in Immunofluorescence, Immunohistochemistry and Western Blot research applications.
Clonality : Monoclonal
Clone ID : RM2L37
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide
Purification: Protein A/G purified from cell culture supernatant
Dilution Range: IF: 1:50-1:200, IHC: 1:100-1:200, WB: 1:1000-1:2000
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: IGHG2
Uniprot ID: IGHG2_HUMAN
Function Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen.
Protein Name Immunoglobulin Heavy Constant Gamma 2
Ig Gamma-2 Chain C Region
Ig Gamma-2 Chain C Region Dot
Ig Gamma-2 Chain C Region Til
Ig Gamma-2 Chain C Region Zie
Cellular Localisation Isoform 1: Secreted
Isoform 2: Cell Membrane
Single-Pass Membrane Protein
Alternative Antibody Names Anti-Immunoglobulin Heavy Constant Gamma 2 antibody
Anti-Ig Gamma-2 Chain C Region antibody
Anti-Ig Gamma-2 Chain C Region Dot antibody
Anti-Ig Gamma-2 Chain C Region Til antibody
Anti-Ig Gamma-2 Chain C Region Zie antibody
Anti-IGHG2 antibody

Information sourced from Uniprot.org

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