Function | Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation. |
Protein Name | Histone H1.2Histone H1cHistone H1dHistone H1s-1 |
Database Links | Reactome: R-HSA-140342Reactome: R-HSA-2559584 |
Cellular Localisation | NucleusChromosomeMainly Localizes In EuchromatinDistribution Goes In Parallel With Dna Concentration |
Alternative Antibody Names | Anti-Histone H1.2 antibodyAnti-Histone H1c antibodyAnti-Histone H1d antibodyAnti-Histone H1s-1 antibodyAnti-H1-2 antibodyAnti-H1F2 antibodyAnti-HIST1H1C antibody |
Information sourced from Uniprot.org