| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit monoclonal anti-Recombinant-Growth/Differentiation Factor 3 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | RM2K40 |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium Azide |
| Purification: | Protein A/G purified from cell culture supernatant |
| Dilution Range: | WB: 1:1000-1:2000 |
| Storage Instruction: | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
| Gene Symbol: | GDF3 |
| Gene ID: | 9573 |
| Uniprot ID: | GDF3_HUMAN |
| Function | Growth factor involved in early embryonic development and adipose-tissue homeostasis. During embryogenesis controls formation of anterior visceral endoderm and mesoderm and the establishment of anterior-posterior identity through a receptor complex comprising the receptor ACVR1B and the coreceptor CRIPTO. Regulates adipose-tissue homeostasis and energy balance under nutrient overload in part by signaling through the receptor complex based on ACVR1C and CRIPTO/Cripto. |
| Protein Name | Growth/Differentiation Factor 3Gdf-3 |
| Database Links | |
| Cellular Localisation | SecretedCytoplasmMainly Accumulated In The Cytoplasm |
| Alternative Antibody Names | Anti-Growth/Differentiation Factor 3 antibodyAnti-Gdf-3 antibodyAnti-GDF3 antibodyAnti-UNQ222 antibodyAnti-PRO248 antibody |
Information sourced from Uniprot.org
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