| Short Description : | Chicken monoclonal anti-Recombinant-GAD65/67 (Full-Length) for use in ICC and IHC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | ICC/IHC |
| Host: | Chicken |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | L127/12 |
| Isotype: | IgY |
| Conjugation: | FL550 Ex: 550 nm, Em: 575 nm |
| Concentration: | 0.5 mg/mL |
| Purification: | Purified by affinity chromatography |
| Dilution Range: | IHC 1:100ICC 1:100 |
| Formulation: | 1X PBS, 0.05% Sodium Azide pH 7.4 |
| Storage Instruction: | Aliquot and store at ≤-20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap. |
| Gene Symbol: | GAD1 |
| Gene ID: | 2571 |
| Uniprot ID: | DCE1_HUMAN |
| Immunogen: | Fusion protein amino acids 1-594 (full-length) of human GAD67 (accession number Q99259) produced recombinantly in E. Coli |
| Immunogen Region: | Full-Length |
| Immunogen Sequence: | Human |
| Specificity: | Cross-reacts with GAD25, GAD44 and GAD65/GAD2 |
| Function | Catalyzes the synthesis of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) with pyridoxal 5'-phosphate as cofactor. Isoform 3: Enzymatically inactive as glutamate decarboxylase. |
| Protein Name | Glutamate Decarboxylase 167 Kda Glutamic Acid DecarboxylaseGad-67Glutamate Decarboxylase 67 Kda Isoform |
| Database Links | Reactome: R-HSA-888568Reactome: R-HSA-888590Reactome: R-HSA-9022927 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Glutamate Decarboxylase 1 antibodyAnti-67 Kda Glutamic Acid Decarboxylase antibodyAnti-Gad-67 antibodyAnti-Glutamate Decarboxylase 67 Kda Isoform antibodyAnti-GAD1 antibodyAnti-GAD antibodyAnti-GAD67 antibody |
Information sourced from Uniprot.org