Post Translational Modifications | Acetylated by ELP3 at Lys-403.acetylation inhibits its homodimerization and enzyme activity. Deacetylated by SIRT2 at Lys-403.deacetylation stimulates its enzyme activity. |
Function | Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis. |
Protein Name | Glucose-6-Phosphate 1-DehydrogenaseG6pd |
Database Links | Reactome: R-HSA-5628897Reactome: R-HSA-71336Reactome: R-HSA-9818028 |
Cellular Localisation | CytoplasmCytosolMembranePeripheral Membrane Protein |
Alternative Antibody Names | Anti-Glucose-6-Phosphate 1-Dehydrogenase antibodyAnti-G6pd antibodyAnti-G6PD antibody |
Information sourced from Uniprot.org