| Host: |
Rabbit |
| Applications: |
IHC/WB |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : |
Rabbit monoclonal antibody anti-Recombinant-F2/Prothrombin is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality : |
Monoclonal |
| Clone ID : |
RM1H36 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.01M PBS |
| Purification: |
Protein A/G purified from cell culture supernatant |
| Dilution Range: |
IHC: 1:50-1:100 |
| Storage Instruction: |
Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
| Function | Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing. Activates coagulation factor XI (F11).activation is promoted by the contact with negatively charged surfaces. Triggers the production of pro-inflammatory cytokines, such as MCP-1/CCL2 and IL8/CXCL8, in endothelial cells. |
| Protein Name | ProthrombinCoagulation Factor Ii Cleaved Into - Activation Peptide Fragment 1 - Activation Peptide Fragment 2 - Thrombin Light Chain - Thrombin Heavy Chain |
| Database Links | Reactome: R-MMU-140837Reactome: -MMU-140875Reactome: -MMU-159740Reactome: -MMU-159763Reactome: -MMU-159782Reactome: -MMU-202733Reactome: -MMU-375276Reactome: -MMU-416476Reactome: -MMU-456926Reactome: -MMU-76009Reactome: -MMU-977606 |
| Alternative Antibody Names | Anti-Prothrombin antibodyAnti-Coagulation Factor Ii Cleaved Into - Activation Peptide Fragment 1 - Activation Peptide Fragment 2 - Thrombin Light Chain - Thrombin Heavy Chain antibodyAnti-F2 antibodyAnti-Cf2 antibody |
Information sourced from Uniprot.org
