Anti-Recombinant-F2/Prothrombin antibody [RM1H36] (STJA0023327)

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STJA0023327
£309.50 - £472.50
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Host: Rabbit
Applications: IHC/WB
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal antibody anti-Recombinant-F2/Prothrombin is suitable for use in Immunohistochemistry and Western Blot research applications.
Clonality : Monoclonal
Clone ID : RM1H36
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.01M PBS
Purification: Protein A/G purified from cell culture supernatant
Dilution Range: IHC: 1:50-1:100
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: F2
Gene ID: 14061
Uniprot ID: THRB_MOUSE
Function Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing. Activates coagulation factor XI (F11).activation is promoted by the contact with negatively charged surfaces. Triggers the production of pro-inflammatory cytokines, such as MCP-1/CCL2 and IL8/CXCL8, in endothelial cells.
Protein Name Prothrombin
Coagulation Factor Ii Cleaved Into - Activation Peptide Fragment 1 - Activation Peptide Fragment 2 - Thrombin Light Chain - Thrombin Heavy Chain
Database Links Reactome: R-MMU-140837
Reactome: -MMU-140875
Reactome: -MMU-159740
Reactome: -MMU-159763
Reactome: -MMU-159782
Reactome: -MMU-202733
Reactome: -MMU-375276
Reactome: -MMU-416476
Reactome: -MMU-456926
Reactome: -MMU-76009
Reactome: -MMU-977606
Alternative Antibody Names Anti-Prothrombin antibody
Anti-Coagulation Factor Ii Cleaved Into - Activation Peptide Fragment 1 - Activation Peptide Fragment 2 - Thrombin Light Chain - Thrombin Heavy Chain antibody
Anti-F2 antibody
Anti-Cf2 antibody

Information sourced from Uniprot.org