| Post Translational Modifications | Acetylated by PCAF/KAT2 (in vitro). Sumoylation on Lys-40 is enhanced by phosphorylation at Ser-45 and represses transcriptional activity. Phosphorylation on Ser-45 enhances sumoylation on Lys-40 thus repressing transcriptional activity. |
| Function | Orphan receptor that acts as a transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements. Induces the expression of PERM1 in the skeletal muscle. |
| Protein Name | Estrogen-Related Receptor GammaErr Gamma-2Estrogen Receptor-Related Protein 3Nuclear Receptor Subfamily 3 Group B Member 3 |
| Database Links | Reactome: R-HSA-383280 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Estrogen-Related Receptor Gamma antibodyAnti-Err Gamma-2 antibodyAnti-Estrogen Receptor-Related Protein 3 antibodyAnti-Nuclear Receptor Subfamily 3 Group B Member 3 antibodyAnti-ESRRG antibodyAnti-ERR3 antibodyAnti-ERRG2 antibodyAnti-KIAA0832 antibodyAnti-NR3B3 antibody |
Information sourced from Uniprot.org
