| Post Translational Modifications | Phosphorylation at Ser-87 and Ser-105 recruits NCOA1. |
| Function | Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1/ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. Isoform 2: Lacks ligand binding ability and has no or only very low ERE binding activity resulting in the loss of ligand-dependent transactivation ability. |
| Protein Name | Estrogen Receptor BetaEr-BetaNuclear Receptor Subfamily 3 Group A Member 2 |
| Database Links | Reactome: R-HSA-1257604Reactome: R-HSA-2219530Reactome: R-HSA-383280Reactome: R-HSA-6811558Reactome: R-HSA-8939211Reactome: R-HSA-9009391 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Estrogen Receptor Beta antibodyAnti-Er-Beta antibodyAnti-Nuclear Receptor Subfamily 3 Group A Member 2 antibodyAnti-ESR2 antibodyAnti-ESTRB antibodyAnti-NR3A2 antibody |
Information sourced from Uniprot.org
