| Function | The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3).this then triggers calcium ion release into the cytosol. |
| Protein Name | Muscarinic Acetylcholine Receptor M2 |
| Database Links | Reactome: R-HSA-390648Reactome: R-HSA-418594Reactome: R-HSA-8856825Reactome: R-HSA-8856828 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinPostsynaptic Cell MembranePhosphorylation In Response To Agonist Binding Promotes Receptor Internalization |
| Alternative Antibody Names | Anti-Muscarinic Acetylcholine Receptor M2 antibodyAnti-CHRM2 antibody |
Information sourced from Uniprot.org
