Anti-Recombinant-chimeric-CD83-Nb-Fc antibody (STJA0038460)
SPECIFICATIONS
ClonalityMonoclonal
Host293F Cells
ConjugationUnconjugated
ImmunogenPurified recombinant Human PD-L1
General Information
| Short Description | 293f Cells monoclonal anti-Recombinant-chimeric-Cd83 antigen-Nb-Fc for use in ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA |
| Host | 293F Cells |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Recombinant Expression and Affinity purified |
| Dilution Range | ELISA 1:5000-100000 |
| Formulation | Phosphate-buffered solution |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CD83 |
| Gene ID | 9308 |
| Uniprot ID | CD83_HUMAN |
| Immunogen | Purified recombinant Human PD-L1 |
| Specificity | This recombinant monoclonal antibody can detects endogenous levels of CD274/PD-L1 protein. |
Additional Info
| Post Translational Modifications | Glycosylated when expressed on activated dendritic cells. |
| Function | Transmembrane glycoprotein predominantly found on the surface of many immune cells including dendritic cells or lymphocytes that plays various roles in immune response regulation. Plays an essential role in CD4(+) T-selection, differentiation and stability by regulating the activity of the major E3 ubiquitin ligase responsible for controlling MHCII trafficking MARCHF8. Also inhibits MARCHF1 association with MHCII or CD86 to prevent their ubiquitination and subsequent degradation. In addition, acts as an important modulator of protective responses against acute infections. |
| Protein Name | Cd83 AntigenHcd83B-Cell Activation ProteinCell Surface Protein Hb15Cd Antigen Cd83 |
| Database Links | |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Cd83 Antigen antibodyAnti-Hcd83 antibodyAnti-B-Cell Activation Protein antibodyAnti-Cell Surface Protein Hb15 antibodyAnti-Cd Antigen Cd83 antibodyAnti-CD83 antibody |
Information sourced from Uniprot.org