| Host: | 293F Cells |
| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | 293f Cells monoclonal anti-Recombinant-chimeric-Cd70 antigen-Nb-Fc for use in ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Conjugation: | Unconjugated |
| Formulation: | Phosphate-buffered solution |
| Purification: | Recombinant Expression and Affinity purified |
| Concentration: | Lot specific |
| Dilution Range: | ELISA 1:5000-100000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CD70 |
| Gene ID: | 970 |
| Uniprot ID: | CD70_HUMAN |
| Specificity: | This recombinant monoclonal antibody can detects endogenous levels of CD70 protein. |
| Immunogen: | Purified recombinant Human CD70 |
| Function | Expressed at the plasma membrane of B cells, it is the ligand of the CD27 receptor which is specifically expressed at the surface of T cells. The CD70-CD27 signaling pathway mediates antigen-specific T cell activation and expansion which in turn provides immune surveillance of B cells. |
| Protein Name | Cd70 AntigenCd27 LigandCd27-LTumor Necrosis Factor Ligand Superfamily Member 7Cd Antigen Cd70 |
| Database Links | Reactome: R-HSA-5669034 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Cd70 Antigen antibodyAnti-Cd27 Ligand antibodyAnti-Cd27-L antibodyAnti-Tumor Necrosis Factor Ligand Superfamily Member 7 antibodyAnti-Cd Antigen Cd70 antibodyAnti-CD70 antibodyAnti-CD27L antibodyAnti-CD27LG antibodyAnti-TNFSF7 antibody |
Information sourced from Uniprot.org