Anti-Recombinant-CDT1 antibody [RM2P30] (STJA0026291)

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STJA0026291
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Host: Rabbit
Applications: IF/IHC/IP/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal anti-Recombinant-Dna Replication Factor Cdt1 for use in IF, IHC, IP and WB in Human samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : RM2P30
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium Azide
Purification: Protein A/G purified from cell culture supernatant
Dilution Range: IF: 1:50-1:200, IHC: 1:100-1:200, IP: 1:20-1:50, WB: 1:1000-1:2000
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: CDT1
Gene ID: 81620
Uniprot ID: CDT1_HUMAN
Function Required for both DNA replication and mitosis. DNA replication licensing factor, required for pre-replication complex assembly. Cooperates with CDC6 and the origin recognition complex (ORC) during G1 phase of the cell cycle to promote the loading of the mini-chromosome maintenance (MCM) complex onto DNA to generate pre-replication complexes (pre-RC). Required also for mitosis by promoting stable kinetochore-microtubule attachments. Potential oncogene.
Protein Name Dna Replication Factor Cdt1
Double Parked Homolog
Dup
Database Links Reactome: R-HSA-68867
Reactome: R-HSA-68949
Reactome: R-HSA-68962
Reactome: R-HSA-69052
Reactome: R-HSA-69205
Cellular Localisation Nucleus
Chromosome
Centromere
Kinetochore
Transiently Localizes To Kinetochores During Prometaphase And Metaphase
Alternative Antibody Names Anti-Dna Replication Factor Cdt1 antibody
Anti-Double Parked Homolog antibody
Anti-Dup antibody
Anti-CDT1 antibody

Information sourced from Uniprot.org

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