Host: | Rabbit |
Applications: | IHC/IP/WB |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit monoclonal antibody anti-Recombinant-Cyclin-Dependent Kinase Inhibitor 1c is suitable for use in Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
Clonality : | Monoclonal |
Clone ID : | RM1X91 |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | 0.01M PBS |
Purification: | Protein A/G purified from cell culture supernatant |
Dilution Range: | IHC: 1:50-1:100 |
Storage Instruction: | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Gene Symbol: | CDKN1C |
Gene ID: | 1028 |
Uniprot ID: | CDN1C_HUMAN |
Function | Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non-proliferative state throughout life. |
Protein Name | Cyclin-Dependent Kinase Inhibitor 1cCyclin-Dependent Kinase Inhibitor P57P57kip2 |
Database Links | Reactome: R-HSA-69231Reactome: R-HSA-9661069 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Cyclin-Dependent Kinase Inhibitor 1c antibodyAnti-Cyclin-Dependent Kinase Inhibitor P57 antibodyAnti-P57kip2 antibodyAnti-CDKN1C antibodyAnti-KIP2 antibody |
Information sourced from Uniprot.org