Anti-Recombinant-CDCA5 antibody [RM2P18] (STJA0026279)

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STJA0026279
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Host: Rabbit
Applications: FC/IF/IHC/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal antibody anti-Recombinant-Sororin is suitable for use in Flow Cytometry, Immunofluorescence, Immunohistochemistry and Western Blot research applications.
Clonality : Monoclonal
Clone ID : RM2P18
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide
Purification: Protein A/G purified from cell culture supernatant
Dilution Range: FCM: 1:20-1:100, IF: 1:50-1:200, IHC: 1:100-1:200, WB: 1:1000-1:2000
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: CDCA5
Gene ID: 113130
Uniprot ID: CDCA5_HUMAN
Function Regulator of sister chromatid cohesion in mitosis stabilizing cohesin complex association with chromatin. May antagonize the action of WAPL which stimulates cohesin dissociation from chromatin. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Required for efficient DNA double-stranded break repair.
Protein Name Sororin
Cell Division Cycle-Associated Protein 5
P35
Database Links Reactome: R-HSA-2467813
Reactome: R-HSA-2468052
Reactome: R-HSA-2500257
Cellular Localisation Nucleus
Chromosome
Cytoplasm
Associates With Nuclear Chromatin From S Phase Until Metaphase And Is Released In The Cytoplasm Upon Nuclear Envelope Breakdown
Alternative Antibody Names Anti-Sororin antibody
Anti-Cell Division Cycle-Associated Protein 5 antibody
Anti-P35 antibody
Anti-CDCA5 antibody

Information sourced from Uniprot.org

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