Anti-Recombinant-CD50/ICAM3 antibody [RM1U60] (STJA0024440)

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STJA0024440
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Short Description :Rabbit monoclonal anti-Recombinant-Intercellular Adhesion Molecule 3 for use in IHC, IP and WB in Human and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications:IHC/IP/WB
Host:Rabbit
Reactivity:Human/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :RM1U60
Isotype:IgG
Conjugation:Unconjugated
Purification:Protein A/G purified from cell culture supernatant
Dilution Range:IHC: 1:50-1:100
Formulation:0.01M PBS
Storage Instruction:Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol:ICAM3
Gene ID:3385
Uniprot ID:ICAM3_HUMAN
Post Translational Modifications Upon stimulation by a physiologic stimuli becomes rapidly and transiently phosphorylated on serine residues. N-glycosylated.glycans consist of a mixture of tri- and tetra-antennary complex-type chains and high-mannose chains.
Function ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM3 is also a ligand for integrin alpha-D/beta-2. In association with integrin alpha-L/beta-2, contributes to apoptotic neutrophil phagocytosis by macrophages.
Protein Name Intercellular Adhesion Molecule 3
Icam-3
Cdw50
Icam-R
Cd Antigen Cd50
Database Links Reactome: R-HSA-198933
Reactome: R-HSA-216083
Reactome: R-HSA-5621575
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Intercellular Adhesion Molecule 3 antibody
Anti-Icam-3 antibody
Anti-Cdw50 antibody
Anti-Icam-R antibody
Anti-Cd Antigen Cd50 antibody
Anti-ICAM3 antibody

Information sourced from Uniprot.org

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