Anti-Recombinant-CD40 antibody [PTR1379] (STJA0038903)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1k
ImmunogenPurified recombinant human CD40.
General Information
| Short Description | Mouse monoclonal anti-Recombinant-Tumor Necrosis Factor Receptor Superfamily Member 5 for use in FC and ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC/ELISA |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | PTR1379 |
| Isotype | IgG1k |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Recombinant Expression and Affinity purified |
| Dilution Range | ELISA 1:5000-100000FC 1-2 Mu g/Test |
| Formulation | Phosphate-buffered solution |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CD40 |
| Gene ID | 958 |
| Uniprot ID | TNR5_HUMAN |
| Immunogen | Purified recombinant human CD40. |
| Specificity | This recombinant monoclonal antibody can detects endogenous levels of CD40 protein. |
Additional Info
| Function | Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 5B-Cell Surface Antigen Cd40Bp50Cd40l ReceptorCdw40Cd Antigen Cd40 |
| Database Links | Reactome: R-HSA-198933 P25942-1Reactome: R-HSA-5668541 P25942-1Reactome: R-HSA-5676594 P25942-1 |
| Cellular Localisation | Isoform I: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform Ii: Secreted |
| Alternative Antibody Names | Anti-Tumor Necrosis Factor Receptor Superfamily Member 5 antibodyAnti-B-Cell Surface Antigen Cd40 antibodyAnti-Bp50 antibodyAnti-Cd40l Receptor antibodyAnti-Cdw40 antibodyAnti-Cd Antigen Cd40 antibodyAnti-CD40 antibodyAnti-TNFRSF5 antibody |
Information sourced from Uniprot.org