| Short Description : | Rabbit monoclonal anti-Recombinant-CD34 for use in IHC and IF in Human, Mouse, Rat and Monkey samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IHC/IF |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat/Monkey |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | SR0541 |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Purification: | Affinity purification |
| Dilution Range: | IHC/IF (H, M, R, Mk) 1:500-1:1000 |
| Formulation: | PBS with 0.15% ProClin300, 100 Mu g/mL BSA and 50% glycerol. |
| Storage Instruction: | Store at-20C for up to one year, and avoid repeated freeze-thaw cycles. |
| Gene Symbol: | CD34 |
| Gene ID: | 947 |
| Uniprot ID: | CD34_HUMAN |
| Immunogen: | KLH conjugated Synthetic peptide corresponding to Human CD34 |
| Post Translational Modifications | Highly glycosylated. Phosphorylated on serine residues by PKC. |
| Function | Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins. |
| Protein Name | Hematopoietic Progenitor Cell Antigen Cd34Cd Antigen Cd34 |
| Database Links | Reactome: R-HSA-198933 P28906-1 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Hematopoietic Progenitor Cell Antigen Cd34 antibodyAnti-Cd Antigen Cd34 antibodyAnti-CD34 antibody |
Information sourced from Uniprot.org
