Host: | Rabbit |
Applications: | IHC/IF |
Reactivity: | Human/Mouse/Rat/Monkey |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit monoclonal antibody anti-Recombinant-CD34 is suitable for use in Immunohistochemistry and Immunofluorescence research applications. |
Clonality : | Monoclonal |
Clone ID : | SR0541 |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.15% ProClin300, 100 Mu g/mL BSA and 50% glycerol. |
Purification: | Affinity purification |
Dilution Range: | IHC/IF (H, M, R, Mk) 1:500-1:1000 |
Storage Instruction: | Store at-20C for up to one year, and avoid repeated freeze-thaw cycles. |
Gene Symbol: | CD34 |
Gene ID: | 947 |
Uniprot ID: | CD34_HUMAN |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human CD34 |
Post Translational Modifications | Highly glycosylated. Phosphorylated on serine residues by PKC. |
Function | Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins. |
Protein Name | Hematopoietic Progenitor Cell Antigen Cd34Cd Antigen Cd34 |
Database Links | Reactome: R-HSA-198933 P28906-1 |
Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
Alternative Antibody Names | Anti-Hematopoietic Progenitor Cell Antigen Cd34 antibodyAnti-Cd Antigen Cd34 antibodyAnti-CD34 antibody |
Information sourced from Uniprot.org