Anti-Recombinant-CD280/MRC2 antibody [RM2K61] (STJA0025926)

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STJA0025926
£309.50 - £472.50
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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal antibody anti-Recombinant-C-Type Mannose Receptor 2 is suitable for use in Western Blot research applications.
Clonality : Monoclonal
Clone ID : RM2K61
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide
Purification: Protein A/G purified from cell culture supernatant
Dilution Range: WB: 1:1000-1:2000
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: MRC2
Gene ID: 9902
Uniprot ID: MRC2_HUMAN
Post Translational Modifications N-glycosylated.
Function May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover. May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs).
Protein Name C-Type Mannose Receptor 2
C-Type Lectin Domain Family 13 Member E
Endocytic Receptor 180
Macrophage Mannose Receptor 2
Urokinase-Type Plasminogen Activator Receptor-Associated Protein
Upar-Associated Protein
Urokinase Receptor-Associated Protein
Cd Antigen Cd280
Database Links Reactome: R-HSA-1236978
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-C-Type Mannose Receptor 2 antibody
Anti-C-Type Lectin Domain Family 13 Member E antibody
Anti-Endocytic Receptor 180 antibody
Anti-Macrophage Mannose Receptor 2 antibody
Anti-Urokinase-Type Plasminogen Activator Receptor-Associated Protein antibody
Anti-Upar-Associated Protein antibody
Anti-Urokinase Receptor-Associated Protein antibody
Anti-Cd Antigen Cd280 antibody
Anti-MRC2 antibody
Anti-CLEC13E antibody
Anti-ENDO180 antibody
Anti-KIAA0709 antibody
Anti-UPARAP antibody

Information sourced from Uniprot.org