Anti-Recombinant-CD147/BSG antibody [RM1V17] (STJA0024496)

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STJA0024496
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Host: Rabbit
Applications: IF/IHC/IP/WB
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal antibody anti-Recombinant-CD147/BSG is suitable for use in Immunofluorescence, Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
Clonality : Monoclonal
Clone ID : RM1V17
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.01M PBS
Purification: Protein A/G purified from cell culture supernatant
Dilution Range: IF: 1:50-1:200
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: Bsg
Gene ID: 12215
Uniprot ID: BASI_MOUSE
Post Translational Modifications Isoform 1: N-glycosylated. Isoform 2: N-glycosylated. During spermatogenesis, probably deglycosylated during epididymal transit.
Function Isoform 1: Essential for normal retinal maturation and development. Acts as a retinal cell surface receptor for NXNL1 and plays an important role in NXNL1-mediated survival of retinal cone photoreceptors. In association with glucose transporter SLC16A1/GLUT1 and NXNL1, promotes retinal cone survival by enhancing aerobic glycolysis and accelerating the entry of glucose into photoreceptors. Isoform 2: Signaling receptor for cyclophilins, essential for PPIA/CYPA and PPIB/CYPB-dependent signaling related to chemotaxis and adhesion of immune cells. Plays an important role in targeting the monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to the plasma membrane. Acts as a coreceptor for vascular endothelial growth factor receptor 2 (KDR/VEGFR2) in endothelial cells enhancing its VEGFA-mediated activation and downstream signaling. Promotes angiogenesis through EPAS1/HIF2A-mediated up-regulation of VEGFA and KDR/VEGFR2 in endothelial cells. Plays an important role in spermatogenesis.mediates interactions between germ cells and Sertoli cell and is essential for the development/differentiation of germ cells to round spermatids.
Protein Name Basigin
Basic Immunoglobulin Superfamily
Ht7 Antigen
Membrane Glycoprotein Gp42
Cd Antigen Cd147
Database Links Reactome: R-MMU-1474228
Reactome: -MMU-210991
Reactome: -MMU-216083
Reactome: -MMU-433692
Reactome: -MMU-9749641
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type I Membrane Protein
Photoreceptor Inner Segment
Cell Projection
Cilium
Photoreceptor Outer Segment
Isoform 2: Cell Membrane
Endoplasmic Reticulum Membrane
Basolateral Cell Membrane
Alternative Antibody Names Anti-Basigin antibody
Anti-Basic Immunoglobulin Superfamily antibody
Anti-Ht7 Antigen antibody
Anti-Membrane Glycoprotein Gp42 antibody
Anti-Cd Antigen Cd147 antibody
Anti-Bsg antibody

Information sourced from Uniprot.org

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