Function | Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The TF:VIIa complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. |
Protein Name | Tissue FactorTfCoagulation Factor IiiThromboplastinCd Antigen Cd142 |
Database Links | Reactome: R-HSA-140834Reactome: R-HSA-9031628 |
Cellular Localisation | Isoform 1: MembraneSingle-Pass Type I Membrane ProteinIsoform 2: Secreted |
Alternative Antibody Names | Anti-Tissue Factor antibodyAnti-Tf antibodyAnti-Coagulation Factor Iii antibodyAnti-Thromboplastin antibodyAnti-Cd Antigen Cd142 antibodyAnti-F3 antibody |
Information sourced from Uniprot.org